참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 5-Chlorosalicylic Acid | HCID 9447 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 용매 | Heptane | HCID 8900 | — |
| 생성물 | 5-Chloro-2-hydroxybenzoyl chloride | HCID 12863233 | 99.3% |
반응 단계
A solution of 5-chloro-2-hydroxy-benzoic acid (20.0 g, 116 mmol) in heptane (232 mL, 0.5 M) was treated with thionyl chloride (25.4 mL, 348 mmol) and heated to 60° C. for 6 h. After cooling to room temperature, the solution was concentrated under reduced pressure to give 5-chloro-2-hydroxy-benzoyl chloride as a thick yellow oil (22 g) which was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07189749B2 |
|---|
| 출처 데이터셋 | uspto-grants-2007_03 |
|---|
| ORD ID | ord-a2eab2155d4c4b518cbf2bcd1b497a70 |
|---|
| 출처 메모 | uspto-grants-2007_03 |
|---|
