P-Anisidine → 1-(4-Methoxyphenyl)-1,3,8-triazaspiro[4.5]decan-4-one

HRID 458144노트

반응식

HRID 458144 반응식
C(N1CCC(=O)CC1)C1C=CC=CC=1.[CH3:15][O:16][C:17]1[CH:22]=[CH:21][C:20]([NH2:23])=[CH:19][CH:18]=1.FC1C=CC(N2[C:35]3([CH2:40][CH2:39][NH:38][CH2:37][CH2:36]3)[C:34](=[O:41])[NH:33][CH2:32]2)=CC=1>>[CH3:15][O:16][C:17]1[CH:22]=[CH:21][C:20]([N:23]2[C:35]3([CH2:40][CH2:39][NH:38][CH2:37][CH2:36]3)[C:34](=[O:41])[NH:33][CH2:32]2)=[CH:19][CH:18]=1

참가 물질

4

반응물 3

HCID 7732P-AnisidineHCID 192201-Benzyl-4-piperidoneHCID 939151-(4-Fluorophenyl)-1,3,8-triazaspiro(4.5)decan-4-one

생성물 1

HCID 132402171-(4-Methoxyphenyl)-1,3,8-triazaspiro[4.5]decan-4-one

실험 절차

This compound was prepared from 1-benzyl-4-piperidone and 4-methoxy-phenyl amine in analogy of the procedure described for the synthesis of 1-(4-fluoro-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one. 1-(4-Methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one was obtained as colorless solid: MS (ISP): 262.1 MH+.

출처 및 근거

ORD 기록
ord-a104a049944947798054786fc7915b85
출처 데이터셋
uspto-grants-2007_03
특허 번호
US07189850B2

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