Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → Methyl (2S)-2-(2,3,4-trifluoroanilino)propionate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2,3,4-Trifluoroaniline | HCID 77468 | — |
| 반응물 | Methyl 2-chloropropanoate, (R)- | HCID 149593 | — |
| 촉매 | Tetrahexylammonium chloride | HCID 80021 | — |
| 생성물 | Methyl (2S)-2-(2,3,4-trifluoroanilino)propionate | HCID 10125210 | — |
반응 단계
In accordance with the process of Example 2, a condensation reaction was performed by using 2,3,4-trifluoroaniline (100 mg), potassium carbonate (188 mg), methyl (2R)-chloropropionate (92 mg) and tetrahexylammonium chloride (40 mg). As the result of the analysis by reversed phase HPLC with the use of the compound of Example 1 as a specimen, the product corresponded to 56 mg (36%) of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07189847B2 |
| 출처 데이터셋 | uspto-grants-2007_03 |
| ORD ID | ord-fa10b7da2f6c432c96677422272918ed |
| 출처 메모 | uspto-grants-2007_03 |