Benzyl Bromide → 7-Benzyl-8-bromo-3-methylxanthine

HRID 458632노트

반응식

HRID 458632 반응식
[Br:1][C:2]1[NH:10][C:9]2[C:8](=[O:11])[NH:7][C:6](=[O:12])[N:5]([CH3:13])[C:4]=2[N:3]=1.[CH2:14](Br)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH2:14]([N:10]1[C:9]2[C:8](=[O:11])[NH:7][C:6](=[O:12])[N:5]([CH3:13])[C:4]=2[N:3]=[C:2]1[Br:1])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

참가 물질

3

반응물 2

HCID 7498Benzyl BromideHCID 15487978-bromo-3-methyl-3,7-dihydro-1H-purine-2,6-dione

생성물 1

HCID 8361527-Benzyl-8-bromo-3-methylxanthine

실험 절차

8-Bromo-3-methyl-3,7-dihydropurine-2,6-dione and benzyl bromide were reacted and purified as described in the General procedure G, step A, to afford 77A.

후처리

  1. custompurified

출처 및 근거

ORD 기록
ord-5c5fedc3df8b401382154178b16ca767
출처 데이터셋
uspto-grants-2007_03
특허 번호
US07192952B2

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