Phenacyl bromide → 7-Benzyl-8-bromo-3-methyl-1-(2-oxo-2-phenylethyl)-3,7-dihydropurine-2,6-dione

HRID 458633노트

반응식

HRID 458633 반응식
[CH2:1]([N:8]1[C:16]2[C:15](=[O:17])[NH:14][C:13](=[O:18])[N:12]([CH3:19])[C:11]=2[N:10]=[C:9]1[Br:20])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:22][C:23]([C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)=[O:24]>>[CH2:1]([N:8]1[C:16]2[C:15](=[O:17])[N:14]([CH2:22][C:23](=[O:24])[C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[C:13](=[O:18])[N:12]([CH3:19])[C:11]=2[N:10]=[C:9]1[Br:20])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 6259Phenacyl bromideHCID 8361527-Benzyl-8-bromo-3-methylxanthine

생성물 1

HCID 225085767-Benzyl-8-bromo-3-methyl-1-(2-oxo-2-phenylethyl)-3,7-dihydropurine-2,6-dione

실험 절차

7-Benzyl-8-bromo-3-methyl-3,7-dihydropurine-2,6-dione (77A) and 2-bromoacetophenone were reacted and purified as described in the General procedure G, Step B, to afford 77B.

후처리

  1. custompurified

출처 및 근거

ORD 기록
ord-3fc9abfe894145c18013b4938b4be9d5
출처 데이터셋
uspto-grants-2007_03
특허 번호
US07192952B2

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