4-Butylphenol → (2S)-3-{4-[3-(4-Butyl-phenoxy)-prop-1-ynyl]-phenyl}-2-methoxy-propionic acid

HRID 459077노트

반응식

HRID 459077 반응식
C([O:3][C:4](=[O:19])[C@@H:5]([O:17][CH3:18])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]#[C:14][CH2:15]Cl)=[CH:9][CH:8]=1)C.[CH3:20][CH2:21][CH2:22][CH2:23][C:24]1[CH:25]=[CH:26][C:27]([OH:30])=[CH:28][CH:29]=1>>[CH2:23]([C:24]1[CH:25]=[CH:26][C:27]([O:30][CH2:15][C:14]#[C:13][C:10]2[CH:9]=[CH:8][C:7]([CH2:6][C@H:5]([O:17][CH3:18])[C:4]([OH:3])=[O:19])=[CH:12][CH:11]=2)=[CH:28][CH:29]=1)[CH2:22][CH2:21][CH3:20]

참가 물질

3

반응물 2

HCID 154204-ButylphenolHCID 58822943(2S)-3-[4-(3-Chloro-prop-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester

생성물 1

HCID 58822860(2S)-3-{4-[3-(4-Butyl-phenoxy)-prop-1-ynyl]-phenyl}-2-methoxy-propionic acid

실험 절차

The title compound was prepared from (2S)-3-[4-(3-Chloro-prop-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 5, Step A and 4-n-butylphenol in a manner analogous to that described for Example 5, Step B. MS(ES) for C23H26O4 [M−H]−: 365.2

출처 및 근거

ORD 기록
ord-0bfe33132e6f41e4b38e0f54744a4d01
출처 데이터셋
uspto-grants-2007_03
특허 번호
US07192982B2

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