Benzyl-4-hydroxyphenylketone → (2S)-2-Methoxy-3-{4-[5-(4-phenylacetyl-phenoxy)-pent-1-ynyl]-phenyl}-propionic acid
반응식
C([O:3][C:4](=[O:21])[CH:5]([O:19][CH3:20])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]#[C:14][CH2:15][CH2:16][CH2:17]Br)=[CH:9][CH:8]=1)C.C([C:29]1[CH:34]=[C:33]([OH:35])[CH:32]=[CH:31][C:30]=1[C:36]([C:38]1C=CC(O)=CC=1CC1C=CC=CC=1)=[O:37])C1C=CC=CC=1>>[CH3:20][O:19][C@@H:5]([CH2:6][C:7]1[CH:8]=[CH:9][C:10]([C:13]#[C:14][CH2:15][CH2:16][CH2:17][O:35][C:33]2[CH:34]=[CH:29][C:30]([C:36](=[O:37])[CH2:38][C:7]3[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=3)=[CH:31][CH:32]=2)=[CH:11][CH:12]=1)[C:4]([OH:3])=[O:21]참가 물질
3
실험 절차
The title compound was prepared from 3-[4-(5-Bromo-pent-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 24, Step A and benzyl-4-hydroxyphenylketone in a manner analogous to that described for Example 24, Step B. MS(ES) for C29H25O5[M−H]−:455.2.
출처 및 근거
- ORD 기록
- ord-5ebec48347574836aae59a315dc78fbd
- 출처 데이터셋
- uspto-grants-2007_03
- 특허 번호
- US07192982B2
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