Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
7-Hydroxyflavone → (2S)-2-Methoxy-3-{4-[3-(4-oxo-2-phenyl-4H-chromen-7-yloxy)-propoxy]-phenyl}-propionic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 7-Hydroxyflavone | HCID 5281894 | — |
| 반응물 | (2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acid | HCID 69424952 | — |
| 생성물 | (2S)-2-Methoxy-3-{4-[3-(4-oxo-2-phenyl-4H-chromen-7-yloxy)-propoxy]-phenyl}-propionic acid | HCID 58822836 | — |
반응 단계
The title compound was prepared from (2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acid linked to Wang's Resin (Example 94, Step D) via Mitsunobu coupling with 7-hydroxyflavone and cleavage from the resin (Standard Procedure G) gave an oily solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07192982B2 |
| 출처 데이터셋 | uspto-grants-2007_03 |
| ORD ID | ord-7a4feb1f8f80404081c313555e183b4e |
| 출처 메모 | uspto-grants-2007_03 |