[4-(3-Bromopropoxy)phenyl]phenylmethanone → 3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-3-methyl-phenyl}-2-methoxy-propionic acid
반응식
C([O:3][C:4](=[O:17])[CH:5]([O:15][CH3:16])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[C:9]([CH3:14])[CH:8]=1)C.Br[CH2:19][CH2:20][CH2:21][O:22][C:23]1[CH:28]=[CH:27][C:26]([C:29]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)=[O:30])=[CH:25][CH:24]=1>>[C:29]([C:26]1[CH:25]=[CH:24][C:23]([O:22][CH2:21][CH2:20][CH2:19][O:13][C:10]2[CH:11]=[CH:12][C:7]([CH2:6][CH:5]([O:15][CH3:16])[C:4]([OH:3])=[O:17])=[CH:8][C:9]=2[CH3:14])=[CH:28][CH:27]=1)(=[O:30])[C:31]1[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=1참가 물질
3
실험 절차
A mixture of 3-(4-Hydroxy-3-methyl-phenyl)-2-methoxy-propionic acid ethyl ester and from Example 162, Step E and [4-(3-Bromo-propoxy)-phenyl]-phenyl-methanone were treated under standard condition I to give the title product.
출처 및 근거
- ORD 기록
- ord-42236658d61e42238c672c051545ac35
- 출처 데이터셋
- uspto-grants-2007_03