Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Aminobenzimidazole → N-(4-Methoxybenzyl)-3H-benzo[d]imidazol-5-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Aminobenzimidazole | HCID 13623 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 4-Methoxybenzaldehyde | HCID 31244 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 생성물 | N-(4-Methoxybenzyl)-3H-benzo[d]imidazol-5-amine | HCID 53496067 | — |
반응 단계
Alternatively the compound was synthesized starting from benzimidazol-5-amine (2.66 g; 20 mmol; 1 eq.), 4-methoxybenzaldehyde (3.26 g; 2.9 ml; 24 mmol; 1.2 eq.), NaBH4 (1.14 g; 30 mmol; 1.5 eq.) and 5 N NaOH (20 ml; 100 mmol; 5 eq.) according to method 2; Yield: 4.53 g (89.5%); MS m/z: 254.3 [M+H]+
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08541596B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-ee3de9ca086b48009106c748d999d6cc |
| 출처 메모 | uspto-grants-2013_09 |