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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 459375생성일: 2026년 10월 24일

3-Fluorophenol → 3-{3-[2-(3-Fluoro-phenoxy)-ethoxy]-phenyl}-2-methoxy-propionic acid

https://huagongshe.com/reaction/459375

반응식

참여 물질

역할이름HCID투입량
반응물3-FluorophenolHCID 9743—
반응물(2S)-2-methoxy-3-[4-(3-phenoxy propoxy)-phenyl]-propionic acidHCID 58822897—
반응물3-[3-(2-Bromo-ethoxy)-phenyl]-2-methoxy-propionic acid methyl esterHCID 69423413—
생성물3-{3-[2-(3-Fluoro-phenoxy)-ethoxy]-phenyl}-2-methoxy-propionic acidHCID 18443589—

반응 단계

The title compound was prepared from 3-fluoro-phenol and 3-[3-(2-bromo-ethoxy)-phenyl]-2-methoxy-propionic acid methyl ester (Example 351, Step 1) via the same procedure used for the preparation of (2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid (Example-285, Step 1). The enatiomers were separated by chiral HPLC. MS (ES) for C18H19FO5 [M−H]−: 333.1.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07192982B2
출처 데이터셋uspto-grants-2007_03
ORD IDord-cae8449b18434d6690315dac77587237
출처 메모uspto-grants-2007_03