Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → HCID 178478161, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 5-(Bromomethyl)-2,1,3-benzothiadiazole | HCID 591004 | — |
| 반응물 | N-(4-Chlorobenzyl)-3H-benzo[d]imidazol-5-amine | HCID 67444221 | — |
| 생성물 | HCID 178478161 | HCID 178478161 | — |
반응 단계
The compound was synthesized starting from N-(4-chlorobenzyl)benzimidazol-5-amine (258 mg; 1 mmol; 1 eq.), (benzo-[c][1,2,5]-thiadiazol-6-yl)methylbromide (252 mg; 1.1 mmol; 1.1 eq.) and K2CO3 (152 mg; 1.1 mmol; 1.1 eq.) according to method 6; Yield: 0.151 g (37.2%); MS m/z: 406.4/408.3 [M+H]+; 1H-NMR (500 MHz, DMSO d6): δ 4.77 (s, 2H); 4.88 (s, 2H); 6.73-6.79 (m, 2H); 7.32-7.38 (m, 5H); 7.69 (dd, 1H, 4J=1.5 Hz, 3J=9.2 Hz); 7.86 (s, 1H); 7.92 (s, 1H); 8.05 (d, 1H, 3J=9.2 Hz); 11.87 (br s, 1H); HPLC (METHOD [A]): rt 15.88 min (95.9%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08541596B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-34b0eb815bfd4cba8af6cb481c4baf2d |
| 출처 메모 | uspto-grants-2013_09 |