Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(4-Methyl-2-(4-(trifluoromethyl)phenyl)-1,3-thiazol-5-yl)methanol → 4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carbaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (4-Methyl-2-(4-(trifluoromethyl)phenyl)-1,3-thiazol-5-yl)methanol | HCID 2783005 | — |
| 촉매 | HCID 178418406 | HCID 178418406 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carbaldehyde | HCID 2782899 | — |
반응 단계
A mixture of {4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methanol (intermediate 1, 2.52 g) in chloroform (200 ml) was treated with manganese dioxide (17.3 g) and the reaction mixture stirred for 2.5 hours. The reaction was filtered through Celite™ and the filtrate evaporated to give the title compound as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07196107B2 |
| 출처 데이터셋 | uspto-grants-2007_03 |
| ORD ID | ord-38597ac01097477aaa879bc75291a459 |
| 출처 메모 | uspto-grants-2007_03 |