Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diphenyl carbonate → N-[2-Methyl-3-[3-(1-piperidinylmethyl)phenoxy]propyl]hydrazine carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diphenyl carbonate | HCID 7597 | — |
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 2-Methyl-3-[3-(1-piperidinylmethyl)phenoxy]-1-propanamine | HCID 13790609 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N-[2-Methyl-3-[3-(1-piperidinylmethyl)phenoxy]propyl]hydrazine carboxamide | HCID 13657331 | — |
반응 단계
2.2 g (8 mmol) of 2-methyl-3-[3-(1-piperidinylmethyl)phenoxy]-1-propanamine in 20 ml of ethanol are stirred together with 1.9 g (8 mmol) of diphenylcarbonate at room temperature for 12 hours. 4 g of hydrazine hydrate is then added to the solution and the reaction mixture is heated under reflux for one hour. Isolation of the product is carried out as described in Example 1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04727081 |
| 출처 데이터셋 | uspto-grants-1988_02 |
| ORD ID | ord-1a0aab0702614837a64963489ec21c3d |
| 출처 메모 | uspto-grants-1988_02 |