Acetic acid 3-benzyloxycarbonylamino-4-oxo-azetidin-2-yl ester → Acetic acid 3-amino-4-oxo-azetidin-2-yl ester
반응식
C(OC([NH:11][CH:12]1[C:15](=[O:16])[NH:14][CH:13]1[O:17][C:18](=[O:20])[CH3:19])=O)C1C=CC=CC=1>[Pd].C(OCC)(=O)C>[NH2:11][CH:12]1[C:15](=[O:16])[NH:14][CH:13]1[O:17][C:18](=[O:20])[CH3:19]참가 물질
4
실험 절차
Acetic acid 3-benzyloxycarbonylamino-4-oxo-azetidin-2-yl ester (100 mg, 0.36 mmol) was hydrogenated on a Parr shaker over 10% palladium on carbon (100 mg) in ethyl acetate (20 ml) at 50 psi for 5 h. The mixture was filtered through Celite and evaporated. Acetic acid 3-amino-4-oxo-azetidin-2-yl ester was obtained in quantitative yield.
후처리
- filtrationThe mixture was filtered through Celite
- customevaporated
출처 및 근거
- ORD 기록
- ord-3cfe61c790c5448d851567369623ad4d
- 출처 데이터셋
- uspto-grants-2007_03
- 특허 번호
- US07196099B2
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