Ethyl 2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)-8-nonenoate → 10-[3,17beta-Dihydroxyestra-1,3,5(10)-trien-7alpha-yl]-2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)decanoic acid

참여 물질

역할	이름	HCID	투입량
반응물	Ethyl 2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)-8-nonenoate	HCID 12048018	—
반응물	3-Methoxy-7alpha-(2-propenyl)estra-1,3,5(10)-trien-17beta-ol	HCID 69414807	—
생성물	10-[3,17beta-Dihydroxyestra-1,3,5(10)-trien-7alpha-yl]-2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)decanoic acid	HCID 53318530	—

반응 단계

Starting with the 3-methoxy-7α-(2-propenyl)estra-1,3,5(10)-trien-17β-ol prepared in Example 13 and ethyl 2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)-8-nonenoate prepared separately, the same procedure as shown in Example 13 was repeated to give 10-[3,17β-dihydroxyestra-1,3,5(10)-trien-7α-yl]-2-(3,3,4,4,5,5,6,6,6-nonafluorohexyl)decanoic acid.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US07196081B2
출처 데이터셋	uspto-grants-2007_03
ORD ID	ord-97a653d0ace3423e9958c9e09aa5695b
출처 메모	uspto-grants-2007_03