Boron tribromide → 3-(7-Hydroxybenzo(b)furan-2-yl)-5-methyl-1,2,4-oxadiazole

HRID 460570노트

반응식

HRID 460570 반응식
C[O:2][C:3]1[C:8]2[O:9][C:10]([C:12]3[N:16]=[C:15]([CH3:17])[O:14][N:13]=3)=[CH:11][C:7]=2[CH:6]=[CH:5][CH:4]=1.B(Br)(Br)Br>>[OH:2][C:3]1[C:8]2[O:9][C:10]([C:12]3[N:16]=[C:15]([CH3:17])[O:14][N:13]=3)=[CH:11][C:7]=2[CH:6]=[CH:5][CH:4]=1

참가 물질

3

반응물 2

HCID 25134Boron tribromideHCID 227293143-(7-Methoxybenzo(b)furan-2-yl)-5-methyl-1,2,4-oxadiazole

생성물 1

HCID 227290843-(7-Hydroxybenzo(b)furan-2-yl)-5-methyl-1,2,4-oxadiazole수율 94%

실험 절차

By the reactions in the same manner as in Starting Material Synthesis Example 5 using 3-(7-methoxybenzo(b)furan-2-yl)-5-methyl-1,2,4-oxadiazole (1.7 g) and boron tribromide (6.5 ml), the title compound (1.5 g) was obtained as white crystals.

출처 및 근거

ORD 기록
ord-3878e395a3f54d56a2a3a1c46e1da399
출처 데이터셋
uspto-grants-2007_03
특허 번호
US07196199B2

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