4-(3,4-Dichloro-phenyl)-piperidine hydrochloride → HCID 69497907, 화합물

반응식

[CH2:1]([O:5][C:6]1[CH:7]=[C:8]([CH:16]=[CH:17][CH:18]=1)[CH:9]=[C:10]1[CH2:15][CH2:14][O:13][C:11]1=[O:12])[C@H:2]1[O:4][CH2:3]1.[Cl:19][C:20]1[CH:21]=[C:22]([CH:27]2[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]2)[CH:23]=[CH:24][C:25]=1[Cl:26]>>[ClH:19].[Cl:19][C:20]1[CH:21]=[C:22]([CH:27]2[CH2:32][CH2:31][N:30]([CH2:3][C@H:2]([OH:4])[CH2:1][O:5][C:6]3[CH:7]=[C:8]([CH:16]=[CH:17][CH:18]=3)[CH:9]=[C:10]3[CH2:15][CH2:14][O:13][C:11]3=[O:12])[CH2:29][CH2:28]2)[CH:23]=[CH:24][C:25]=1[Cl:26]

참가 물질

반응물 2

HCID 162442724-(3,4-Dichloro-phenyl)-piperidine hydrochloride

HCID 86585646HCID 86585646, 화합물

생성물 1

HCID 69497907HCID 69497907, 화합물

실험 절차

In the same manner as in Example 425, the title compound was synthesized from (S)-α-(3-glycidyloxybenzylidene)-γ-butyrolactone and 4-(3,4-dichlorophenyl)piperidine, melting point 147–149° C.

출처 및 근거

ORD 기록: ord-6f421695f42541aca022fd1f7f6b1bd3
출처 데이터셋: uspto-grants-2007_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07196199B2

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