p-Toluenesulfonic acid → HCID 20367322, 화합물
반응식
C([O:3][C:4](=O)[CH:5]=[C:6]([NH2:10])OCC)C.C1(C)C=CC(S(O)(=O)=O)=CC=1.[Br:23][C:24]1[CH:25]=[C:26]([CH:30]=[CH:31][CH:32]=1)[CH2:27][NH:28][NH2:29]>C(O)C>[NH2:10][C:6]1[NH:29][N:28]([CH2:27][C:26]2[CH:30]=[CH:31][CH:32]=[C:24]([Br:23])[CH:25]=2)[C:4](=[O:3])[CH:5]=1참가 물질
5
실험 절차
20.5 g of β-amino-β-ethoxyacrylic acid ethyl ester together with 1.5 g of p-toluenesulphonic acid were dissolved in 200 ml of ethanol. 26 g of m-bromobenzylhydrazine were added dropwise to this solution, under nitrogen. After stirring for two hours, the mixture was left to stand overnight and the compound identified above, which had separated out as a precipitate, was filtered off and recrystallised from ethanol. Melting Point: 160°, 12 g (35%).
후처리
- waitthe mixture was left
- waitto stand overnight
- customhad separated out as a precipitate
- filtrationwas filtered off
- customrecrystallised from ethanol
출처 및 근거
- ORD 기록
- ord-2bee44edf3834bf3a5f2005a4d656082
- 출처 데이터셋
- uspto-grants-1977_12
- 특허 번호
- US04061653
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