Quinoline → 3-Buten-2-ol, 1,1-dimethoxy-2-methyl-

HRID 460959노트

반응식

HRID 460959 반응식
[CH3:1][O:2][CH:3]([O:9][CH3:10])[C:4]([CH3:8])([OH:7])[C:5]#[CH:6].N1C2C(=CC=CC=2)C=CC=1.[H][H]>[Pd]>[CH3:1][O:2][CH:3]([O:9][CH3:10])[C:4]([CH3:8])([OH:7])[CH:5]=[CH2:6]

참가 물질

5

반응물 3

HCID 7047QuinolineHCID 128752274,4-Dimethoxy-3-methyl-but-1-yn-3-olHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 110080503-Buten-2-ol, 1,1-dimethoxy-2-methyl-

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

198 G. of 4,4-dimethoxy-3-methyl-but-1-yn-3-ol are dissolved in 960 ml. of high-boiling petroleum ether and, after the addition of 19.35% palladium catalyst and 19.3 g. of quinoline, hydrogenated under normal conditions. After the uptake of 33.5.1. of hydrogen, the hydrogenation is stopped. The catalyst is filtered off. The filtrate is evaporated under reduced pressure. The remaining 4,4-dimethoxy-3-methyl-but-1-en-3-ol boils, after rectification, at 70°-72° C./18 mm Hg.

후처리

  1. filtrationThe catalyst is filtered off
  2. customThe filtrate is evaporated under reduced pressure
  3. customat 70°-72° C.

출처 및 근거

ORD 기록
ord-62fcc790771141dca290e5a598283223
출처 데이터셋
uspto-grants-1977_12
특허 번호
US04061656

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