N-(4-nitrophenyl)pentanamide → N-(4-aminophenyl)pentanamide

HRID 461019

반응식

HRID 461019 반응식
[N+:1]([C:4]1[CH:16]=[CH:15][C:7]([NH:8][C:9](=[O:14])[CH2:10][CH2:11][CH2:12][CH3:13])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([NH:8][C:9](=[O:14])[CH2:10][CH2:11][CH2:12][CH3:13])=[CH:15][CH:16]=1

참가 물질

4

반응물 1

HCID 3762929N-(4-nitrophenyl)pentanamide

생성물 1

HCID 1725711N-(4-aminophenyl)pentanamide

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A solution of 4'-nitrovaleranilide (13.33 g., 0.06 mole) in absolute ethanol (750 ml.) is hydrogenated over 10% palladium on charcoal (2 g.) until the theoretical absorption is achieved. The catalyst is removed and the solvent is removed in vacuo. The residue is recrystallized from butyl chloride to yield 9.0 g., m.p. 81°-83° C.

후처리

  1. customThe catalyst is removed
  2. customthe solvent is removed in vacuo
  3. customThe residue is recrystallized from butyl chloride
  4. customto yield 9.0 g

출처 및 근거

ORD 기록
ord-1657976fc8b14bb1ae6485729ff31a32
출처 데이터셋
uspto-grants-1977_12
특허 번호
US04061763

연결된 노트

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