Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromo-4'-chloro-3'-sulfamoylacetophenone → 4-(4-Chloro-3-sulfamoylphenyl)-2-isopropylimino-3-methyl-1,3-thiazolidine-4-ol-hydrobromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bromo-4'-chloro-3'-sulfamoylacetophenone | HCID 12952390 | — |
| 반응물 | 1-Methyl-3-isopropylthiourea | HCID 14229900 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 4-(4-Chloro-3-sulfamoylphenyl)-2-isopropylimino-3-methyl-1,3-thiazolidine-4-ol-hydrobromide | HCID 22760466 | — |
반응 단계
6.1 g of 2-bromo-4'-chloro-3'-sulfamoylacetophenone were heated with 2.4 g of 1-methyl-3-isopropylthiourea in 50 ml of acetone for 10 minutes to 40° C, the separating oil was triturated to form crystals and the crystalline suspension was stirred for 1 hour at room temperature. Colorless solid body: melting point: 195° C (decomposition).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04061761 |
| 출처 데이터셋 | uspto-grants-1977_12 |
| ORD ID | ord-32104b1699e44898ad55d752a12d86bc |
| 출처 메모 | uspto-grants-1977_12 |