Dimethylamine → HCID 22760438, 화합물

HRID 461191노트

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HRID 461191 반응식
[CH3:1][NH:2][CH3:3].CO.[Cl:6][C:7]1[CH:12]=[CH:11][C:10]([C:13](=[O:15])[CH3:14])=[CH:9][C:8]=1[S:16](Cl)(=[O:18])=[O:17]>O>[Cl:6][C:7]1[CH:12]=[CH:11][C:10]([C:13](=[O:15])[CH3:14])=[CH:9][C:8]=1[S:16](=[O:17])(=[O:18])[N:2]([CH3:3])[CH3:1]

참가 물질

5

반응물 3

HCID 674DimethylamineHCID 887MethanolHCID 126197955-Acetyl-2-chlorobenzene-1-sulfonyl chloride

생성물 1

HCID 22760438HCID 22760438, 화합물

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
60 °C

실험 절차

To a stirred mixture of 10 ml of 40% dimethyl amine solution and 60 ml of methanol, there were added, portionswise, 5.1 g of 4'-chloro-3'-chlorosulfonylacetophenone, so that the reaction temperature did not exceed 30° C. The reaction mixture was stirred for 3 hours at room temperature and 15 minutes at 60° C. After cooling, the reaction mixture was poured into 200 ml of water and the crystals were filtered off. Melting point: 108° C.

후처리

  1. additionwere added
  2. customdid not exceed 30° C
  3. temperatureAfter cooling
  4. filtrationthe crystals were filtered off

출처 및 근거

ORD 기록
ord-ab96505f96444dcd888e4ac1b02ab2e3
출처 데이터셋
uspto-grants-1977_12
특허 번호
US04061761

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