Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrogen Bromide → 2-Bromo-5-(trifluoromethyl)benzenamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrogen Bromide | HCID 260 | — |
| 반응물 | 3-(Trifluoromethyl)aniline | HCID 7375 | — |
| 반응물 | Bromine | HCID 24408 | — |
| 촉매 | Iron | HCID 23925 | — |
| 생성물 | 2-Bromo-5-(trifluoromethyl)benzenamine | HCID 67989 | — |
반응 단계
To 161.0 g of m-aminobenzotrifluoride and 10.0 g of iron filings is added, dropwise, with agitation at 35°-40°, 160.0 g of bromine, using a slow stream of nitrogen to sweep out the evolved hydrogen bromide. Subsequently, the mixture is agitated for an additional 2 hours and then distilled in vacuo to give 4-bromo-3-aminobenzotrifluoride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04062846 |
| 출처 데이터셋 | uspto-grants-1977_12 |
| ORD ID | ord-07101a937af44b0ca9bf8d6e74b4b500 |
| 출처 메모 | uspto-grants-1977_12 |