Hydrogen Peroxide → N-Anthraquinon-1-ylacetamide

HRID 461399

반응식

HRID 461399 반응식
[NH:1]([C:5]1[C:18]2[CH2:17][C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[C:10](=[O:19])[C:9]=2[CH:8]=[CH:7][CH:6]=1)[C:2]([CH3:4])=[O:3].[O-:20][Si]([O-])=O.[Na+].[Na+].OO>O>[NH:1]([C:5]1[C:18]2[C:17](=[O:20])[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[C:10](=[O:19])[C:9]=2[CH:8]=[CH:7][CH:6]=1)[C:2]([CH3:4])=[O:3]

참가 물질

5

반응물 3

HCID 784Hydrogen Peroxide2회HCID 23266Sodium SilicateHCID 213936134-Acetamino-anthrone

생성물 1

HCID 76760N-Anthraquinon-1-ylacetamide수율 94.3%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

125.5 g (0.5 mole) of 4-acetamino-anthrone in 1.5 liters of water are warmed to 70°. 50 ml of sodium water glass are added (d = 1.35) and 400 ml of a hydrogen peroxide solution which contains 80 g of H2O2 per liter are then allowed to run in dropwise in the course of 1 hour. Appropriately, a slight stream of nitrogen is passed over the surface during the reaction. The mixture is then stirred at between 70° and 90° C until no further starting material is found in a sample which is withdrawn and examined by thin layer chromatography. In the course of the oxidation, the suspension has developed an intense yellow color. The suspension is filtered and the product washed until neutral. After drying, 125 g of 1-acetamino-anthraquinone with a melting point of 221° C are obtained.

후처리

  1. customdropwise in the course of 1 hour
  2. customAppropriately, a slight stream of nitrogen is passed over the surface during the reaction
  3. customis withdrawn
  4. filtrationThe suspension is filtered
  5. washthe product washed until neutral
  6. customAfter drying

출처 및 근거

ORD 기록
ord-2b5037d0ab4c47f2852d2fe302e8849a
출처 데이터셋
uspto-grants-1977_12
특허 번호
US04062875

연결된 노트

불러오는 중…