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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 461515생성일: 2026년 10월 25일

n-(3-Aminopropyl)benzamide → 1-[1(2-((5-Methyl-4-imidazolyl)methylthio)ethylamino)-2-nitrovinylamino]-3-[N'-cyano-N"-(2-(2-pyridylmethylthio)ethyl)guanidino]propane

https://huagongshe.com/reaction/461515

반응식

참여 물질

역할이름HCID투입량
반응물n-(3-Aminopropyl)benzamideHCID 238993—
반응물N-cyano-N'[2-(2-pyridylmethylthio)ethyl]-S-methylisothioureaHCID 12889408—
반응물1-nitro-2-methylthio-2-{2-[(4-methyl-1H-imidazol-5-yl)methylthio]ethylamino}ethyleneHCID 70456864—
생성물1-[1(2-((5-Methyl-4-imidazolyl)methylthio)ethylamino)-2-nitrovinylamino]-3-[N'-cyano-N"-(2-(2-pyridylmethylthio)ethyl)guanidino]propaneHCID 178433675—

반응 단계

1-Nitro-2-methylthio-2-[2-((5-methyl-4-imidazolyl)methylthio)ethylamino]ethylene was reacted with 3-benzoylaminopropylamine and the product was hydrolysed under acidic conditions and reacted with N-cyano-N'-[2-(2-pyridylmethylthio)ethyl]-S-methylisothiourea to give the title compound.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04062967
출처 데이터셋uspto-grants-1977_12
ORD IDord-ed0e3c16588e4479b7510923c016c8f7
출처 메모uspto-grants-1977_12