Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl isothiocyanate → 2-(Methylaminothioxomethyl)-N-[3-[3-(1-piperidinylmethyl)phenoxy]-propyl]-hydrazine carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl isothiocyanate | HCID 11167 | — |
| 반응물 | N-(3-{3-[(Piperidin-1-yl)methyl]phenoxy}propyl)hydrazinecarboxamide | HCID 13657330 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-(Methylaminothioxomethyl)-N-[3-[3-(1-piperidinylmethyl)phenoxy]-propyl]-hydrazine carboxamide | HCID 13657344 | — |
반응 단계
0.5 g (6.6 mmol) of methylisothiocyanate are added to 1.0 g (3.3 mmol) of N-[3-[3-(1-piperidinylmethyl) phenoxy]propyl]-hydrazine carboxamide in 20 ml of THF and the mixture is stirred at room temperature for 12 hours. The precipitate obtained is filtered off and recrystallised from ethanol. The analytical values are summarized in Table I.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04727081 |
| 출처 데이터셋 | uspto-grants-1988_02 |
| ORD ID | ord-43d9b13e76d64c13a9297ad2f6e9042c |
| 출처 메모 | uspto-grants-1988_02 |