Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → Orotic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Urea | HCID 1176 | — |
| 반응물 | Trichloroacetyl chloride | HCID 6420 | — |
| 반응물 | 4,4,4-Trichloro-3-oxobutanoyl chloride | HCID 21391724 | — |
| 생성물 | Orotic Acid | HCID 967 | — |
반응 단계
To recap, this invention involves: converting trichloroacetyl chloride with ketone to γ,γ ,γ -trichloroacetoacetyl chloride, adding the reaction mixture to urea dissolved in a polar organic solvent, e.g., acetic acid; evaporating out the resulting 6-trichloromethyluracil; and hydrolyzing the 6-trichloromethyluracil to form orotic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04064126 |
| 출처 데이터셋 | uspto-grants-1977_12 |
| ORD ID | ord-3be252f833cc47e5a14f6bf37e6b0113 |
| 출처 메모 | uspto-grants-1977_12 |