Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acenaphthenequinone → 9-(Trifluoromethyl)acenaphtho[1,2-b]quinoxaline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acenaphthenequinone | HCID 6724 | — |
| 반응물 | 2,6-Dinitro-4-(trifluoromethyl)aniline | HCID 9936 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 9-(Trifluoromethyl)acenaphtho[1,2-b]quinoxaline | HCID 12624102 | 50% |
반응 단계
Acenaphthenequinone, 9.1 g. (0.05m), and 10.3 g. (0.05m) of 4-amino-3-nitrobenzotrifluoride were hydrogenated at room temperature in 125 ml. of 2B ethanol with 2.5 g. of palladium-on-carbon (5 percent) at 50 psi. After 4 hours three equivalents of hydrogen were absorbed and the temperature rose to 40° C. The catalyst was filtered and the filtrate was diluted with 1.2 l. of ethanol. The reaction was completed by refluxing the ethanolic solution for about 1 hour. The precipitated product was collected to yield about 8 g. (50 percent yield) of 9-(trifluoromethyl)acenaphtho[1,2-b]quinoxaline, mp = 185°-186° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04064127 |
| 출처 데이터셋 | uspto-grants-1977_12 |
| ORD ID | ord-0ad9a4b1ec14493b94feb95eda397d2f |
| 출처 메모 | uspto-grants-1977_12 |