Ammonia → Benzo[4,5]thiazolo[2,3-c][1,2,4]triazol-3(2H)-one

반응식

[NH:1]([C:3]1[S:4][C:5]2[CH:11]=[CH:10][CH:9]=[CH:8][C:6]=2[N:7]=1)[NH2:2].N[C:13](N)=[O:14].N>>[N:1]1[N:2]=[C:13]([OH:14])[N:7]2[C:6]3[CH:8]=[CH:9][CH:10]=[CH:11][C:5]=3[S:4][C:3]=12

참가 물질

반응물 3

HCID 222Ammonia

HCID 1176Urea

HCID 119882-Benzothiazolinone, hydrazone

생성물 1

HCID 178518874Benzo[4,5]thiazolo[2,3-c][1,2,4]triazol-3(2H)-one

실험 절차

2-Hydrazinobenzothiazole (100 grams) and urea (100 grams) were fused on an oil bath at about 180° C. for about an hour, by which time the molten material had solidified and evolution of ammonia had ceased. The solid thus obtained, the desired s-triazolo(3,4-b)benzothiazol-3-ol, was recrystallized twice from methanol, m.p., 235° C.