참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Potassium Nitrate | HCID 24434 | — |
| 반응물 | 3-Fluorobenzonitrile | HCID 67880 | — |
| 생성물 | 5-Fluoro-2-nitrobenzonitrile | HCID 3756467 | 86.5% |
반응 단계
m-Fluorobenzonitrile (96.8 g., 0.8 mole) is added in two and one-half hours to a mixture of concentrated sulfuric acid (600 ml.) and potassium nitrate (80.9 g., 0.8 mole) at 3°-6° C., then allowed to warm to 25° C. The mixture is poured over cracked ice (3000 ml.), extracted with chloroform (5 × 250 ml.), dried and the solvent removed. The residue is extracted with pentane and dried to give 3-cyano-4-nitrofluorobenzene (115 g., 86.5%) m.p. 102°-104° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04063929 |
|---|
| 출처 데이터셋 | uspto-grants-1977_12 |
|---|
| ORD ID | ord-c7eebc7d266b4a1b8c587f6ff00c2bdf |
|---|
| 출처 메모 | uspto-grants-1977_12 |
|---|
