Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 1-(2,4-Dimethoxyphenyl)ethanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Acetovanillone | HCID 2214 | — |
| 반응물 | Dimethyl Sulfate | HCID 6497 | — |
| 반응물 | Sodium Carbonate | HCID 10340 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 1-(2,4-Dimethoxyphenyl)ethanone | HCID 70016 | — |
반응 단계
10 g of acetovanillone (0.06 mol) was methylated with 10.25 g of dimethyl sulfate (0.083 mol) and 8.0 g of sodium carbonate. The reaction mixture was stirred at 80°-90° C for 2 hr. while 6 ml of water were added dropwise over the last 1.2 hr. Addition of water, acidification, and extraction with benzene produced a nearly quantitative yield of 2,4-dimethoxyacetophenone containing less than 0.3% acetovanillone.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04065504 |
| 출처 데이터셋 | uspto-grants-1977_12 |
| ORD ID | ord-53ad9b6fae294a6cbcb7f7bd0053547c |
| 출처 메모 | uspto-grants-1977_12 |