2-(Chloromethyl)-1-methoxy-4-nitrobenzene → N-methyl-N-(5-nitro-2-methoxybenzyl)N,N-bis(3-formamidopropyl)ammonium chloride

HRID 462151노트

반응식

HRID 462151 반응식
[CH:1]([NH:3][CH2:4][CH2:5][CH2:6][N:7]([CH3:14])[CH2:8][CH2:9][CH2:10][NH:11][CH:12]=[O:13])=[O:2].[N+:15]([C:18]1[CH:19]=[CH:20][C:21]([O:26][CH3:27])=[C:22]([CH:25]=1)[CH2:23][Cl:24])([O-:17])=[O:16]>O>[Cl-:24].[CH3:14][N+:7]([CH2:23][C:22]1[CH:25]=[C:18]([N+:15]([O-:17])=[O:16])[CH:19]=[CH:20][C:21]=1[O:26][CH3:27])([CH2:6][CH2:5][CH2:4][NH:3][CH:1]=[O:2])[CH2:8][CH2:9][CH2:10][NH:11][CH:12]=[O:13]

참가 물질

4

반응물 2

HCID 25293772-(Chloromethyl)-1-methoxy-4-nitrobenzeneHCID 3084810Formamide, N,N'-[(methylimino)di-3,1-propanediyl]bis-

생성물 1

HCID 20336842N-methyl-N-(5-nitro-2-methoxybenzyl)N,N-bis(3-formamidopropyl)ammonium chloride

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Proceeding in a manner similar to that described above in B-8a, 142 parts of N,N-bis(3-formamidopropyl)methylamine and 141 parts of 5-nitro-2-methoxybenzyl chloride were interacted in 115 parts of water to obtain N-methyl-N-(5-nitro-2-methoxybenzyl)-N,N-bis(3-formamidopropyl)ammonium chloride. The product was not isolated but was used directly in solution for reduction of the nitro group.

출처 및 근거

ORD 기록
ord-5b9778496e57456e8370216627ce7be9
출처 데이터셋
uspto-grants-1977_12
특허 번호
US04065500

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