Triethylamine → HCID 20397918, 화합물

HRID 462391노트

반응식

HRID 462391 반응식
[CH2:1]([SH:12])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].Br[CH2:14][CH:15]=[C:16]=[CH:17][CH2:18][CH2:19][C:20]([O:22][CH3:23])=[O:21].C(N(CC)CC)C>C(OCC)C>[C:20]([O:22][CH3:23])(=[O:21])[CH2:19][CH2:18][CH:17]=[C:16]=[CH:15][CH2:14][S:12][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 625701-UndecanethiolHCID 13470498HCID 13470498, 화합물

생성물 1

HCID 20397918HCID 20397918, 화합물수율 32.2%

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

A mixture of 376 mg of undecylmercaptan, 438 mg of methyl 7-bromohepta-4,5-dienoate and 0.278 ml of triethyl amine in 2 ml of diethyl ether were stirred at room temperature for 1 hour. The solvent was removed in vacuo and the residue chromatographed on silica gel eluting with hexane and toluene to give 210 mg of methyl 8-thianonadeca-4,5-dienoate having the following NMR spectrum which was run in deutochloroform solution with TMS as the internal standard.

후처리

  1. customThe solvent was removed in vacuo
  2. customthe residue chromatographed on silica gel eluting with hexane and toluene

출처 및 근거

ORD 기록
ord-329c38f8063747abaf98633411b1332e
출처 데이터셋
uspto-grants-1985_05
특허 번호
US04515727

반응 노트

불러오는 중…