Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Methyl 4-chloro-2-(4-hydroxyphenylamino)benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Dimethyl Sulfate | HCID 6497 | — |
| 반응물 | Boron tribromide | HCID 25134 | — |
| 반응물 | 4-Chloro-2-((4-methoxyphenyl)amino)benzoic acid | HCID 66674 | — |
| 반응물 | 4-Chloro-2-(4-hydroxyphenylamino)benzoic acid | HCID 425423 | — |
| 반응물 | HCID 20225134 | HCID 20225134 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Methyl 4-chloro-2-(4-hydroxyphenylamino)benzoic acid | HCID 20225128 | — |
반응 단계
[I; R=4-Cl, R' and R"=H, Alk=CH3, OH at 4-position] is obtainable by esterification of 4-chloro-2-(4-hydroxyphenylamino)benzoic acid with methanol and hydrochloric acid; or by esterification of 4-chloro-2-(4-methoxyphenylamino)benzoic acid with dimethyl sulfate, followed by de-etherification of the resulting methyl 4-chloro-2-(4-methoxyphenylamino)benzoate with boron tribromide.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04515980 |
| 출처 데이터셋 | uspto-grants-1985_05 |
| ORD ID | ord-a077546466954d6184495be609ecff98 |
| 출처 메모 | uspto-grants-1985_05 |