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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 462661생성일: 2026년 10월 26일

Hydrogen Cyanide → 2-(2-Fluoro-4-trifluoromethylphenylamino)-3-methylbutyronitrile

https://huagongshe.com/reaction/462661

반응식

참여 물질

역할이름HCID투입량
반응물Hydrogen CyanideHCID 768—
반응물IsobutyraldehydeHCID 6561—
반응물2-Chloro-4-trifluoromethylanilineHCID 162001—
반응물2-Fluoro-4-(trifluoromethyl)anilineHCID 2737674—
용매WaterHCID 962—
생성물2-(2-Fluoro-4-trifluoromethylphenylamino)-3-methylbutyronitrileHCID 20283984—

반응 단계

Following the procedure of Example 1, each of 3-chloro-4-aminobenzotrifluoride and 3-fluoro-4-aminobenzotrifluoride is reacted with hydrogen cyanide and isobutyraldehyde, in a neat, initially water-free system, to give the respective nitrile, 2-(2-chloro-4-trifluoro-methylphenylamino)-3-methylbutyronitrile and 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutyronitrile.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04517130
출처 데이터셋uspto-grants-1985_05
ORD IDord-f4fb8e7036e843d7865338e8ca199b44
출처 메모uspto-grants-1985_05