Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chloroform → 5-Hydroxy-4,5-bis-(4-methoxyphenyl)-2-thioxo-3-pyrroline-3-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chloroform | HCID 6212 | — |
| 반응물 | 4,4'-Dimethoxybenzil | HCID 71043 | — |
| 반응물 | 2-Cyanoethanethioamide | HCID 1416277 | — |
| 촉매 | Piperidine | HCID 8082 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 5-Hydroxy-4,5-bis-(4-methoxyphenyl)-2-thioxo-3-pyrroline-3-carbonitrile | HCID 13236226 | — |
반응 단계
16.5 g. 4,4'-Dimethoxybenzil, 6.0 g. cyanothioacetamide and 15 drops of piperidine were boiled for 2 hours in 200 ml. chloroform on a water separator. The yellow precipitate obtained was filtered off with suction, washed with some chloroform and dried at 80° C. and 0.1 mm.Hg for 12 hours. The desired product is obtained in a yield of 17.6 g. in the form of yellow crystals; m.p. 193° C. (decomp.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04517185 |
| 출처 데이터셋 | uspto-grants-1985_05 |
| ORD ID | ord-63f16b988f4143aa98321b2732bbe485 |
| 출처 메모 | uspto-grants-1985_05 |