Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,2-Ethanedione, 1,2-bis(4-chlorophenyl)- → 4,5-Bis-(4-chlorophenyl)-5-hydroxy-2-thioxo-3-pyrroline-3-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,2-Ethanedione, 1,2-bis(4-chlorophenyl)- | HCID 18946 | — |
| 반응물 | 2-Cyanoethanethioamide | HCID 1416277 | — |
| 촉매 | Piperidine | HCID 8082 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 4,5-Bis-(4-chlorophenyl)-5-hydroxy-2-thioxo-3-pyrroline-3-carbonitrile | HCID 13236225 | — |
반응 단계
A suspension of 22.3 g. 4,4'-dichlorobenzil, 6.5 g. 2-cyanothioacetamide, 20 drops of piperidine and 200 ml. chloroform is stirred for 20 hours at ambient temperature. The yellow precipitate obtained is filtered off with suction, well washed with chloroform and dried. There are obtained 22.0 g. of the desired compound in the form of yellow crystals; m.p. 213° C. (decomp.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04517185 |
| 출처 데이터셋 | uspto-grants-1985_05 |
| ORD ID | ord-8d02aad0da4c4edcb6cbbdcdbe59e98d |
| 출처 메모 | uspto-grants-1985_05 |