Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 462916생성일: 2026년 10월 25일
Glutaric Acid → N-[4-(3-aminopropyl)aminobutyl]-2-(9-guanidino-2-nonenamido)-2-hydroxyethanamide
https://huagongshe.com/reaction/462916
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Glutaric Acid | HCID 743 | — |
| 반응물 | Glyoxylylspermidine | HCID 133564 | — |
| 반응물 | HCID 178478605 | HCID 178478605 | — |
| 반응물 | HCID 178479425 | HCID 178479425 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | N-[4-(3-aminopropyl)aminobutyl]-2-(9-guanidino-2-nonenamido)-2-hydroxyethanamide | HCID 178512796 | 38.9% |
반응 단계
A mixture of 206.2 mg (0.84 mmole) of 9-guanidino-2-nonenamide hydrochloride, 291.0 mg (1.00 mmole) of N-[4-(3-aminopropyl)aminobutyl]-2,2-dihydroxyethanamide dihydrochloride, 109.6 mg (0.84 mmole) of glutaric acid and 0.2 ml of water was heated at 60° C. for 24 hours. After completion of the reaction, the reaction mixture was purified in a manner similar to that in Example 1 using CM-Sephadex® C-25 (Na-type) and Sephadex® LH-20 to obtain 135.0 mg (31.1% yield) of a white powder of N-[4-(3-aminopropyl)aminobutyl]-2-(9-guanidino-2-nonenamido-2-hydroxyethanamide trihydrochloride.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US04518532 |
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| 출처 데이터셋 | uspto-grants-1985_05 |
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| ORD ID | ord-dc615805a55a42cf8a30f6d2f2018da6 |
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| 출처 메모 | uspto-grants-1985_05 |
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