2-Iodo-4-(trifluoromethoxy)phenol → 3-cyano-N-(2,4-dimethoxybenzyl)-4-[2-iodo-4-(trifluoromethoxy)phenoxy]-N-1,2,4-thiadiazol-5-ylbenzenesulfonamide
반응식
[I:1][C:2]1[CH:7]=[C:6]([O:8][C:9]([F:12])([F:11])[F:10])[CH:5]=[CH:4][C:3]=1[OH:13].[C:14]([C:16]1[CH:17]=[C:18]([S:23]([N:26]([CH2:32][C:33]2[CH:38]=[CH:37][C:36]([O:39][CH3:40])=[CH:35][C:34]=2[O:41][CH3:42])[C:27]2[S:31][N:30]=[CH:29][N:28]=2)(=[O:25])=[O:24])[CH:19]=[CH:20][C:21]=1F)#[N:15]>>[C:14]([C:16]1[CH:17]=[C:18]([S:23]([N:26]([CH2:32][C:33]2[CH:38]=[CH:37][C:36]([O:39][CH3:40])=[CH:35][C:34]=2[O:41][CH3:42])[C:27]2[S:31][N:30]=[CH:29][N:28]=2)(=[O:25])=[O:24])[CH:19]=[CH:20][C:21]=1[O:13][C:3]1[CH:4]=[CH:5][C:6]([O:8][C:9]([F:11])([F:12])[F:10])=[CH:7][C:2]=1[I:1])#[N:15]참가 물질
3
실험 절차
The title compound was prepared according to Preparation 255 using 2-iodo-4-(trifluoromethoxy)phenol (Preparation 226) and 3-cyano-N-(2,4-dimethoxybenzyl)-4-fluoro-N-1,2,4-thiadiazol-5-ylbenzene sulfonamide (Preparation 68).
출처 및 근거
- ORD 기록
- ord-ee960b5af06541aaab0c5dc39f932de7
- 출처 데이터셋