Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonium Chloride → 4'-Chloro-3-phenylpropiophenone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonium Chloride | HCID 25517 | — |
| 반응물 | Benzenepropanoyl chloride | HCID 64801 | — |
| 반응물 | HCID 178478191 | HCID 178478191 | — |
| 촉매 | Cadmium chloride, dihydrate | HCID 24633 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 4'-Chloro-3-phenylpropiophenone | HCID 247344 | 58% |
반응 단계
Phenylpropionyl chloride (33.7 g) in benzene was added dropwise to a stirred mixture of 4-chlorophenyl magnesium bromide (derived from 38 g of 4-chlorobromobenzene) and cadmium chloride (37 g) in benzene at 0°. The mixture was stirred at room temperature for 6 hours and aqueous ammonium chloride solution then added. Ether extraction yielded p-chlorophenyl phenylethyl ketone (25 g) m.p. 78°-79°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04520007 |
| 출처 데이터셋 | uspto-grants-1985_05 |
| ORD ID | ord-61dbe1b7ada641c0b901f2e585d9aef7 |
| 출처 메모 | uspto-grants-1985_05 |