Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chloro-1,2-dinitrobenzene → ethyl P-methyl-2-nitro-5-chlorophenylphosphinate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chloro-1,2-dinitrobenzene | HCID 33097 | — |
| 반응물 | Diethyl methylphosphonite | HCID 85063 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | ethyl P-methyl-2-nitro-5-chlorophenylphosphinate | HCID 53860251 | — |
반응 단계
To 4-chloro-1,2-dinitrobenzene (13.2 g, 65.0 mmol) dissolved in acetonitrile (150 ml) is added, dropwise, diethyl methylphosphonite (16.0 g, 117.6 mmol). The mixture is stirred at RT for 20 hours, after which it is concentrated. The crude product is purified by column chromatography (developing with 50% ethyl acetate/hexane) to yield ethyl P-methyl-2-nitro-5-chlorophenylphosphinate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04520197 |
| 출처 데이터셋 | uspto-grants-1985_05 |
| ORD ID | ord-cd5e6dca7b5048fab9a1583e2647bcfa |
| 출처 메모 | uspto-grants-1985_05 |