Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thionyl Chloride → 5-Methyl-3-phenylisoxazole-4-carbonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | 5-Methyl-3-phenyl-4-isoxazoloyl carboxylic acid | HCID 20265152 | — |
| 촉매 | Pyridine | HCID 1049 | — |
| 생성물 | 5-Methyl-3-phenylisoxazole-4-carbonyl chloride | HCID 85624 | — |
반응 단계
A mixture of 111.76 g of 5-methyl-3-phenyl-4-isoxazoloyl carboxylic acid, 6 drops of pyridine and 29.5 ml of thionyl chloride is stirred under reflux for 4 hrs. The excess thionyl chloride is evaporated in vacuo. Distillation of the residue yields 113.74 g of yellow liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04544670 |
| 출처 데이터셋 | uspto-grants-1985_10 |
| ORD ID | ord-e5e56676ef5d48e9b65a67a4cd85f5d8 |
| 출처 메모 | uspto-grants-1985_10 |