2-Amino-5-bromo-1,3,4-thiadiazole → (+/-)-N-[2-methyl-3[3-(1-piperidinylmethyl)phenoxy]propyl]-1,3,4-thiadiazole-2,5-diamine

HRID 4638

반응식

HRID 4638 반응식
[CH3:1][CH:2]([CH2:5][O:6][C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([CH2:13][N:14]2[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]2)[CH:8]=1)[CH2:3][NH2:4].Br[C:21]1[S:25][C:24]([NH2:26])=[N:23][N:22]=1>>[CH3:1][CH:2]([CH2:5][O:6][C:7]1[CH:12]=[CH:11][CH:10]=[C:9]([CH2:13][N:14]2[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]2)[CH:8]=1)[CH2:3][NH:4][C:21]1[S:25][C:24]([NH2:26])=[N:23][N:22]=1

참가 물질

3

반응물 2

HCID 36508832-Amino-5-bromo-1,3,4-thiadiazoleHCID 137906092-Methyl-3-[3-(1-piperidinylmethyl)phenoxy]-1-propanamine

생성물 1

HCID 20151492(+/-)-N-[2-methyl-3[3-(1-piperidinylmethyl)phenoxy]propyl]-1,3,4-thiadiazole-2,5-diamine

실험 절차

The compound is prepared by a method analogous to Example 51 from 2-methyl-3-[3-(1-piperidinylmethyl) phenoxy]-1-propanamine and 5-bromo-1,3,4-thiadiazole-2-amine.

출처 및 근거

ORD 기록
ord-c587ea1f6afa47de97166c863f4d86d1
출처 데이터셋
uspto-grants-1988_02
특허 번호
US04727081

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