O-Allylhydroxylamine hydrochloride → 2-Allyloxyimino-2-(3-chloro-4-hydroxyphenyl)acetic acid

HRID 463839노트

반응식

HRID 463839 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([C:9](=O)[C:10]([OH:12])=[O:11])[CH:5]=[CH:6][C:7]=1[OH:8].Cl.[CH2:15]([O:18][NH2:19])[CH:16]=[CH2:17]>>[CH2:15]([O:18][N:19]=[C:9]([C:4]1[CH:5]=[CH:6][C:7]([OH:8])=[C:2]([Cl:1])[CH:3]=1)[C:10]([OH:12])=[O:11])[CH:16]=[CH2:17]

참가 물질

3

반응물 2

HCID 3084724O-Allylhydroxylamine hydrochlorideHCID 129611392-(3-Chloro-4-hydroxyphenyl)-2-oxoacetic acid

생성물 1

HCID 1362107842-Allyloxyimino-2-(3-chloro-4-hydroxyphenyl)acetic acid수율 98.1%

실험 절차

2-(3-Chloro-4-hydroxyphenyl)glyoxylic acid (2 g.) and O-allylhydroxylamine hydrochloride (1.1 g.) were reacted according to a similar manner to that of Preparation 5-2)(a) to give oil of 2-allyloxyimino-2-(3-chloro-4-hydroxyphenyl)acetic acid (syn isomer) (2.5 g.).

후처리

  1. customof Preparation 5-2)(a)

출처 및 근거

ORD 기록
ord-f8d85d1db7b1412fadc04662059775e1
출처 데이터셋
uspto-grants-1985_10
특허 번호
US04544653

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