Selenium Dioxide → Ethyl 2-(2-t-pentyloxycarbonylamino-1,3-thiazol-4-yl)glyoxylate

HRID 463855노트

반응식

HRID 463855 반응식
[C:1]([O:6][C:7]([NH:9][C:10]1[S:11][CH:12]=[C:13]([CH2:15][C:16]([O:18][CH2:19][CH3:20])=[O:17])[N:14]=1)=[O:8])([CH2:4][CH3:5])([CH3:3])[CH3:2].[Se](=O)=[O:22]>>[C:1]([O:6][C:7]([NH:9][C:10]1[S:11][CH:12]=[C:13]([C:15](=[O:22])[C:16]([O:18][CH2:19][CH3:20])=[O:17])[N:14]=1)=[O:8])([CH2:4][CH3:5])([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 24007Selenium DioxideHCID 19978738Ethyl 2-(2-t-pentyloxycarbonylamino-1,3-thiazol-4-yl)acetate

생성물 1

HCID 19978748Ethyl 2-(2-t-pentyloxycarbonylamino-1,3-thiazol-4-yl)glyoxylate수율 70.6%

실험 절차

Ethyl 2-(2-t-pentyloxycarbonylamino-1,3-thiazol-4-yl)acetate (0.3 g.) and selenium dioxide (0.11 g.) were treated according to a similar manner to that of Preparation 6-4) to give brown oil of ethyl 2-(2-t-pentyloxycarbonylamino-1,3-thiazol-4-yl)glyoxylate (0.22 g.).

후처리

  1. customof Preparation 6-4)

출처 및 근거

ORD 기록
ord-a692688ec3e94268a7d845522ad08f6b
출처 데이터셋
uspto-grants-1985_10
특허 번호
US04544653

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