Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 4-Methoxybenzenecarbothioamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 4-Methoxybenzonitrile | HCID 70129 | — |
| 반응물 | Thioacetamide | HCID 2723949 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 4-Methoxybenzenecarbothioamide | HCID 736827 | 75.4% |
반응 단계
A mixture of 53.26 g of anisonitrile and 60.10 g of thioacetamide in 600 ml of dimethylformamide was saturated with dry hydrogen chloride gas while being cooled in an ice bath. The mixture was then distilled on an oil bath at 100° C. After the liquid had been removed, aqueous sodium bicarbonate was added and the solid was collected and recrystallized from toluene, giving 50.47 g of 4-methoxythiobenzamide as a yellow solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04544759 |
| 출처 데이터셋 | uspto-grants-1985_10 |
| ORD ID | ord-e79458266d034204a700be91ab1937be |
| 출처 메모 | uspto-grants-1985_10 |