N,N-Diethyl-1-heptanamine → 4(3-Chlorophenyl)-N,N-diethyl-N-heptyl-2-buten-1-aminium chloride

HRID 464033노트

반응식

HRID 464033 반응식
[Cl:1]C1C=CC=C(CC=CCCl)C=1.Cl[CH:14]([CH2:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[CH:19]=1)[CH:15]=[CH2:16].[CH2:25]([N:27]([CH2:35][CH3:36])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])[CH3:26]>O>[Cl-:1].[Cl:24][C:20]1[CH:19]=[C:18]([CH2:17][CH:14]=[CH:15][CH2:16][N+:27]([CH2:25][CH3:26])([CH2:35][CH3:36])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])[CH:23]=[CH:22][CH:21]=1

참가 물질

5

반응물 3

HCID 12496130N,N-Diethyl-1-heptanamineHCID 202636013-Chloro-4-(3-chlorophenyl)-1-buteneHCID 538104491-Chloro-3-(4-chloro-2-butenyl)benzene

생성물 1

HCID 704471924(3-Chlorophenyl)-N,N-diethyl-N-heptyl-2-buten-1-aminium chloride

시약·촉매·용매 1

HCID 962Water용매

실험 절차

Heat a mixture of 6.0 g (0.03 mole) of 1-chloro-3-(4-chloro-2-butenyl)benzene and 3-chloro-4-(3-chlorophenyl)-1-butene (in a ratio of 4:3) and 5.1 g (0.03 mole) N,N-diethylheptanamine at 100° C. for about 20 hours. Dissolve in 100 ml water and wash with 3×75 ml hexane and then extract with methylene chloride. Dry methylene chloride extract over magnesium sulfate, filter and evaporate the solvent in vacuo to provide the title compound.

후처리

  1. temperatureHeat
  2. washwash with 3×75 ml hexane
  3. extractionextract with methylene chloride
  4. extractionDry methylene chloride extract over magnesium sulfate
  5. filtrationfilter
  6. customevaporate the solvent in vacuo

출처 및 근거

ORD 기록
ord-71f1b03136004ccd85e37aba9d16dd88
출처 데이터셋
uspto-grants-1985_10
특허 번호
US04545995

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