Hydrazine → N'-[(4-cyanophenyl)methylidene]benzenesulfonohydrazide

HRID 464099

반응식

HRID 464099 반응식
[C:1]1([S:7]([NH:10][NH2:11])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:12]([C:14]1[CH:21]=[CH:20][C:17]([CH:18]=O)=[CH:16][CH:15]=1)#[N:13].NN>C(O)C>[C:1]1([S:7]([NH:10][N:11]=[CH:18][C:17]2[CH:20]=[CH:21][C:14]([C:12]#[N:13])=[CH:15][CH:16]=2)(=[O:8])=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

5

반응물 3

HCID 9321HydrazineHCID 65723Benzenesulfonyl hydrazideHCID 660424-Cyanobenzaldehyde

생성물 1

HCID 1474568N'-[(4-cyanophenyl)methylidene]benzenesulfonohydrazide

시약·촉매·용매 1

HCID 702Ethanol용매2회

실험 절차

Benzenesulfonyl hydrazine (20.5 g, 0.12 mole) was dissolved by warming in 110 ml absolute ethanol. p-Cyanobenzaldehyde (15.6 g, 0.12 mole) was separately dissolved in 50 ml of hot ethanol and added to the hydrazine solution. The resulting slurry was refluxed 0.5 hour, cooled and filtered to yield 28.1 g; m.p. 209°-213°. Recrystallization from CH3CN gave purified title product: 23.7 g; m.p. 210°-213°.

후처리

  1. temperatureThe resulting slurry was refluxed 0.5 hour
  2. temperaturecooled
  3. filtrationfiltered
  4. customto yield 28.1 g
  5. customRecrystallization from CH3CN
  6. customgave
  7. custompurified title product

출처 및 근거

ORD 기록
ord-2f3ebd3da2dd45cf834f52d28bad5db4
출처 데이터셋
uspto-grants-1985_10
특허 번호
US04546113

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