2-Amino-5-bromo-1,3,4-thiadiazole → N-[3-[3-(4-Morpholinylmethyl)phenoxy]propyl]-1,3,4-thiadiazole-2.5-diamine

HRID 4643

반응식

HRID 4643 반응식
[N:1]1([CH2:7][C:8]2[CH:9]=[C:10]([CH:16]=[CH:17][CH:18]=2)[O:11][CH2:12][CH2:13][CH2:14][NH2:15])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.Br[C:20]1[S:24][C:23]([NH2:25])=[N:22][N:21]=1>>[N:1]1([CH2:7][C:8]2[CH:9]=[C:10]([CH:16]=[CH:17][CH:18]=2)[O:11][CH2:12][CH2:13][CH2:14][NH:15][C:20]2[S:24][C:23]([NH2:25])=[N:22][N:21]=2)[CH2:2][CH2:3][O:4][CH2:5][CH2:6]1

참가 물질

3

반응물 2

HCID 36508832-Amino-5-bromo-1,3,4-thiadiazoleHCID 133908193-[3-(4-Morpholinylmethyl)phenoxy]1-propanamine

생성물 1

HCID 20151483N-[3-[3-(4-Morpholinylmethyl)phenoxy]propyl]-1,3,4-thiadiazole-2.5-diamine

실험 절차

The compound is prepared by a method analogous to that of Example 51 from 3-[3-(4-morpholinylmethyl)phenoxy]1-propanamine and 5-bromo-1,3,4-thiadiazole-2-amine.

출처 및 근거

ORD 기록
ord-bcd6c58213474e3e95f3d43538841d42
출처 데이터셋
uspto-grants-1988_02
특허 번호
US04727081

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